Fetal Inflammatory Response Of Umbilical And Chorionic Plate Vessels

Fetal response to infection occurs after the maternal response and usually suggests a more well-established infection. It may be attenuated or absent in midgestation, although I have seen significant funisitis as early as 18 weeks of gestation. Funisitis and Vasculitis Gross and Microscopic Funisitis can rarely be grossly identified. The umbilical cord may be quite edematous. Within the extra fluid within the cord substance, large accumulations of neutrophils may be visible as white rings...

Risk Of Maternal Infection During Pregnancy

Varicella can be an extremely serious disease in pregnant women. Fortunately, widespread use of vaccine is likely to decrease the overall incidence of varicella, including during pregnancy, because of individual and herd immunity. Eventually, it is hoped that widespread immunization of children will lead to only rare susceptibility during the childbearing years, as well as little circulation of the wild-type virus. This situation would be projected to make varicella in pregnancy extremely rare,...

References

Dorenbaum A, Cunningham CK, Gelber RD, et al. Two-dose intrapartum newborn nevirapine and standard antiretroviral therapy to reduce perinatal HIV transmission a randomized trial. JAMA 2002 288 189-198. 2. Garcia PM, Kalish LA, Pitt J, et al. Maternal levels of plasma human immunodeficiency virus type 1 RNA and the risk of perinatal transmission. Women and Infants Transmission Study Group. N Engl J Med 1999 341 394-402. 3. Ioannidid JP, Abrams EJ, Ammann A, et al. Perinatal transmission of human...