First, treatment with ICS is costly. Treatment such as that used in ISOLDE would in Denmark cost € 760 (£480) per year. Based on the crude effects in ISOLDE, it thus costs approximately £ 1440 to avoid one exacerbation. In a subsequent analysis of data from the 6-month study by Paggiaro et al. , it was claimed that inhaled fluticasone was cost-effective, and the differences
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