Accelerated Muscular Development Programs

Isometrics Mass Exercises

Isometric Mass is the most revolutionary fitness program in the market right now. It is the great way of training to build muscle in short time and increase the testosterone in the blood, a way that proved to help even 40th and 50th men to overcome their age boundaries and build beautiful muscle and improve their health with less than 30 min training every day. Isometric mass program helped me build muscle with less effort in less time and saved me time and money because the isometric system doesn't need fancy equipment and count only on body weight. The program is divided into basic set of DVDs and bonus set. The basic set cover everything from quick start guide, instructional video library for the isometric techniques, isometric mass workout guide which will save you all your costs you used to pay for trainers and gym. The last basic product is an isometric printable logs to help you keep track of your workout and progress. The bonus part of the isometric mass is very cool because it contain the body weight edition of the isometric system, a great done-for-you meal plan that fits greatly into the isometric system and the last bonus product is a great guide for using supplements which could make you finally understand the art and science of taking supplements. Isometric mass is a great program every muscle builder should have. Continue reading...

Isometrics Mass Summary

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4.9 stars out of 30 votes

Contents: Ebooks, Videos, Meal Plan
Author: Alby Gonzalez
Official Website: isometricsmass.com
Price: $9.00

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My Isometrics Mass Review

Highly Recommended

The very first point I want to make certain that Isometrics Mass definitely offers the greatest results.

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Physique Zero

The name of the author is Alain Gonzalez who is a fitness coach and a long time author. This guy wants to help millions of people all over the world especially those that don't have enough time to train at the GYM. On his prior work, this man wanted to help skinny guys but later noticed that people of all ages, and body sizes needed help to build muscles too. With a busy family life, he believes that you can as well use the little time you have to build muscles and at the same time become fit. With this program, you will eliminate some of the things that you thought mattered the most to build muscles. As a matter of fact, the author dedicated some time to conduct research and later develop a powerful system that is easy to follow and that will help you build muscles without 'GYMing''. Upon purchasing, you will get the main product in form of a downloadable PDF formats. The author has also included some videos to show you exactly what you are supposed to do. This program is for anyone that wants to get leaner, stronger and get more energy with ease regardless of their social status, age and race. Continue reading...

Physique Zero Summary

Contents: Ebooks
Author: Alain Gonzalez
Official Website: projecthypertrophy.com
Price: $15.00

The Muscle Maximizer

The first truly custom, interactive, professional nutrition system proven to explode lean muscle growth without any fat. The systems 4 patented formulas are the true keys to unlocking more muscle growth than you thought possible. Formula 1 is the Sometabolic Customizer You will discover your exact calorie and macronutrient needs to build pure lean muscle using the systems advanced somatotyping techniques. You will also find out exactly what and when to eat based around your weight training regimen to catapult your body into a 24/7 muscle building state. Formula 2 is the Somanabolic Rebuilder This is for your off days. Your recovery nutrition is custom structured to repair and rebuild your broken down muscle tissue quickly. Using unique calorie and macronutrient shifting techniques your muscle recovery is extremely rapid and muscle soreness is often 100 % eliminated. Formula 3 is the ever so important Systematic Nutrabolism This is the key for up to 84% of all your lean muscle growth. Continue reading...

The Muscle Maximizer Summary

Official Website: www.themusclemaximizer.com
Price: $47.00

Skeletal Muscle Development

Glypican-1 expression has been identified during skeletal muscle development (96). During skeletal muscle formation, syndecan-1 levels are high during the proliferation of muscle cells followed by an increase in glypican-1 expression during muscle cell differentiation (82). Both syndecan-1 and glypican-1 function in the signaling of FGF-2. Fibroblast growth factor 2 is a potent stimulator of muscle cell proliferation and a strong inhibitor of muscle cell differentiation. The differences in syndecan-1 and glypican-1 expression suggest that these proteoglycans function in a differential manner in the signaling of FGF-2. Brandan and Larrain (73) hypothesized, based on differences in their in vitro expression in myogenic cell cultures, that syndecan-1 may increase muscle cell proliferation by presenting FGF-2 to its receptor, and glypican may sequester FGF-2 to permit differentiation to proceed. Conclusive evidence has not yet been obtained to support this hypothesis. Syndecans-2 through...

Protein for Bodybuilding

In bodybuilding increased muscle size is produced mainly by extensive weight training, not by eating large amounts of protein. However, weightlifters need about two and a half times the amount of protein of nonexercising individuals about 1.8 g kg day, or about 120 g for a 70-kg person.6 Increased protein requirements should be met by consuming high-quality protein foods, such as eggs, low-fat milk, lean meats, and fish. If the athlete is vegetarian, combining foods carefully (see pp. 19) will provide complete protein for new muscle synthesis. There is usually no need for protein or amino-acid supplements if ample high-quality protein is obtained from dietary sources.6

Mitochondrial function in insulin resistant states

Alternative 31P MRS methods can assess the mitochondrial function by measuring the recovery of the skeletal muscle phosphocreatine (PCr) pool following its depletion by well defined isometric exercise (Arnold et al. 1984 Kemp & Radda 1994 Radda et al. 1995 Newcomer & Boska 1997). This process is coupled with recovery of basal skeletal

Muscle Mass Changes Sarcopenia

As seen in young adults, changes in muscle strength and size in response to resistance training or inactivity are not always related 59, 60 . Resistance exercise can lead to major improvements in function with little or no change in muscle mass, or even in strength 60 . It is generally agreed that the loss of SM mass and function can be prevented by specific intervention

Functional Decline and Aging

Maximal oxygen consumption (VO2max) declines with age at a rate of 3-8 per decade beginning at 30 years of age 30, 31 . While the major contributor to VO2max is lean muscle mass, after correction for muscle mass, there is no important decline in VO2max with aging 32 . Physically active older men have a higher VO2max

Interventions To Improve Functional Status

Most studies demonstrating an improvement in muscle strength have shown its direct relationship to the intensity of the exercise intervention. The data suggest that exercise programs must be high-intensity (70-90 of one repetition maximum) rather than low-intensity (against gravity) in order to produce benefit. The benefit of strength training has been demonstrated to exist even in frail, institutionalized, elderly men and women. After 8 weeks of intensive training in volunteers age 90 years, muscle strength increased by 174 31 and mid-thigh muscle size by 9 4.5 (79). Muscle strength improved by 113 8 following high-intensity exercise training by long-term care residents with a mean age of 87 years 80 . Exercise also improves muscle mass, as measured by computed tomography of the thigh in institutionalized older adults 81 .

Exercise Fitness Training

Deconditioning is very common in FMS patients and it is associated with many FMS symptoms (31). Various types of exercise including stationary cycling, aerobic walking, and aerobic dance have been evaluated (148-152), and it has been determined that aerobic exercise three times a week can reduce TP tenderness (31,153,154). Strength training and aerobic exercise is associated with improvements in pain, TP counts, and disturbed sleep (151,152,155). As indicated, maintenance of exercise programs in FMS tends to be poor (151,152). A systematic review (161) indicates that supervised aerobic exercise training will have beneficial effects on physical capacity and FMS symptoms. Strength training may also be beneficial. More research, per the authors, is needed.

Experimental Disease Models

The Mdr1a mouse model is one of the few genetic disease models that develop a colitic phenotype in the absence of immune dysfunction. This is in contrast to virtually all other genetically targeted mice, which develop colitis as a result of either impaired immune function, a cytokine imbalance, or colitis that can be induced by reconstituting naive (CD4 + CD45Rbhi) T cells into severe combined immunodeficiency (SCID) mice. Most of the experimental models of IBD in mice have inflammation only in the colon and resemble UC. The one striking exception to this is the SAMP1 Yit mouse and the derivative SAMP1 YitFc strain. These mice spontaneously develop a Crohn's-like transmural ileitis as early as 10 weeks of age, accompanied by prominent muscular hypertrophy, fibrosis, and activation of mesenteric lymph node lymphocytes, which produce high levels of interferon g (IFN-g). Furthermore, a subgroup of SAMP1 YitFc mice ( 5 ) also develops perianal fistulating disease.

Growth Hormone and Insulin Like Growth Factor1

Growth hormone (GH) and insulin-like growth factor (IGF)-1 stimulate amino-acid uptake and protein synthesis in muscle and improve myocyte proliferation and differentiation in animal studies 106, 107 . The FDA recently granted accelerated approval for a form of recombinant human GH (rhGH) to treat AIDS wasting. Preliminary reports from Schambelan and co-workers in AIDS patients have all been positive 108-112 . The combined GH and IGF-1 doses used in studies in adult males with HIV-associated weight loss had mixed results in producing a sustained anabolic response 113-120 . In fact, after trauma, the anti-catabolic action of rhGH is associated with a potentially harmful decrease in muscle glutamine production and increased mortality 116 . Use of the rhGH for elderly patients with a low somatomedin C or IGF improved lean muscle mass, but not functional ability. Moreover, frequent side effects were seen 121 . Morley and coworkers 122 demonstrated that rhGH, which is a very expensive...

Elevation in Proinflammatory Cytokines

Normal aging is associated with an increase in the proinflammatory cytokines interleukin (IL)-6 and tumour necrosis factor (TNF)-a 24 and a reduction in muscle mass. Therefore, it is possible that the elevation in proinflammatory cytokines, which can induce proteolysis in skeletal muscle, may contribute to the decline in muscle mass with age. Visser et al. 25 reported that IL-6 and TNF-a concentration were inversely related to muscle mass and muscle strength in 3075 elderly individuals. Furthermore, Greiwe et al. 26 reported that TNF-a in muscle is elevated in frail elders and that resistance training decreased the resting TNF-a concentration. It has also been demonstrated that IL-6 and IGF-1 and their interaction were significant predictors of handgrip strength and muscle power 27 . IGF-1 was an independent predictor of muscle function only in subjects in the lowest IL-6 tertile, suggesting that the effect of IGF-1 on muscle function depends on the IL-6 level 27 . Payette et al. 28...

Interventions to Reverse Sarcopenia Resistance Exercise Training

Resistance exercise training, which involves exercises with high loads ( 80 of maximal force generating capacity) and low repetitions ( 8-10 repetitions), is a potent stimulator of muscle mass accrual 37, 38 and muscle strength gains 39-42 in the elderly. One way in which muscle mass is increased is by an increase in muscle protein synthesis. Yarasheski et al. 10 reported that 2 weeks of resistance training in the elderly increased muscle protein synthesis by 153 . From 16 studies in which men and women performed resistance training (8-12 weeks), the range for the increase in strength was 15.6-134 , with the mean being 58 improvement and the median for the increase in strength being 52.6 43 . Improvements in strength occur via an increase in the ability to activate the muscles maximally (increased motor- unit recruitment and increased motor-unit firing rates) and to an increase in muscle size. During the first 8-12 weeks of resistance exercise training, the increase in the ability to...

Testosterone Replacement

Who had low or borderline low serum testosterone ( 13.9 nmol l 400 ng dl). A small (3 ) increase in lean body mass and no change in grip strength were reported. In an open-labelled trial without a control group, Urban et al. 52 administered 100 mg of testosterone per week over 4 weeks to elderly men with a serum testosterone concentration of 480 ng dl. Significant increases in strength in the hamstrings and quadriceps of both legs were observed. In contrast to the positive benefits observed in most studies, Snyder et al. 53 reported that, despite a 70 increase in testosterone concentration over 36 months in men over the age of 65 (using a testosterone patch), there was no significant improvement in muscle strength despite a significant increase in lean body mass. Thus, from these data it appears that testosterone replacement is likely an effective intervention for reversing sar-copenia. However, whether it is a better and or safer alternative than resistance training remains to be...

Growth Hormone and IGF1

There are three studies that compared growth hormone (GH) administration with resistance training (RT) to RT alone. Yarasheski et al. 58 had men with low serum IGF-1 age 67 years complete 16 weeks of resistance training with GH administration or RT alone. They found no differences in the increase in the rate of vastus lateralis protein synthesis or isotonic and isokinetic strength between groups. Fat-free mass increased more in the RT + GH group than the RT group but this was attributed to an increase in non-contractile protein and fluid retention. Hennessey et al. 59 also reported no effect of GH administration with RT relative to RT alone with regard to strength improvements in elderly individuals (age 71.3 years). Strength improved by 55.6 in the GH + RT group and 47.8 in the RT alone group. Of possible importance, however, was the increase in the proportion of type II muscle fibres seen in the RT + GH group, as type II fibre atrophy and loss are observed in older individuals....

Intervention 2641 Physical Activity

Types of exercise used most frequently in adult cancer patients were aerobic or cardiovascular endurance and occasionally strength training programs 19 . Activities included regular walking, treadmill walking, bicycle ergometry, or bed ergometry for hospitalized patients. Walking is the most common exercise for cancer patients 19, 27 . It is a natural, safe, and tolerable choice that relates directly to daily living and is conducive to AYA lifestyle, particularly if complemented with music or participation with peers. It is important for AYA to participate in activities in which they will experience personal accomplishment. Recreational pursuits are often the most preferred form of activity. Popular options include martial arts, dance, aerobics, swimming, walking, biking, and activities at fitness clubs. Some AYA are able to resume competitive sports, although adaptations may be necessary.

Pseudohypoparathyroidism

PE Irritability poor muscular development and muscle tone abdominal distention hypotonia of all muscles anterior fontanelle open softening of occipital and parietal bones with elastic recoil (craniotabes) frontal bossing enlargement of costochon-dral junctions (rachitic rosary) bowing of legs lineal chest depression along diaphragm (Harrison's groove).

Endocrine Disorders Associated with Myofascial Pain

Hypothyroidism is secondary to a lack of thyroid hormone production levothyroxine (T4) and liothyronine (T3) secondary to a problem with the hypotha-lamic-pituitary-thyroid (HPT) axis. Clinically, the patients are frequently overweight. Their eyelids may be puffy, their voice hoarse. The thyroid gland may be enlarged. Their muscles are stiff, tender, and, on occasion, weak. They may display muscle hypertrophy. TrPs are common. Their primary complaint may be diffuse muscle tenderness. The Achilles reflex may show delayed relaxation. Laboratory testing typically shows low serum thyroxine (T4), free thyroxine index, and a high thyroid-stimulating hormone (TSH) level. Pituitary-adrenal insufficiency typically is found to be caused by adrenal atrophy secondary to tumor, hemorrhage, or even infarction of the pituitary. The presenting symptoms not infrequently include myofascial pain and TrPs. The examination should show poor muscle development, weakness, testicular atrophy, loss of libido,...

Glomerular function Glomerular filtration

Cystatin C is a naturally circulating, low molecular weight, basic protein which is freely filtered by the glomerulus and almost completely reabsorbed and catabolised by tubular cells. Serum levels are independent of age, sex and lean muscle mass. Although levels reflect trends in reduced GFR, particularly

Syndecans

Fibroblast growth factor-2 is a heparin-binding growth factor that stimulates cell proliferation and inhibits cell differentiation. Although FGF can bind to its tyrosine kinase receptor, the low-affinity interaction with heparan sulfate enables the formation of a high-affinity interaction with its receptor, resulting in growth factor mediated signaling at low growth factor concentrations. The interaction of syndecan-1 with FGF has been shown to play a role in skeletal muscle development (42), and wound repair (55). During wound repair, syndecan-1 expression is induced by FGF-2 (56). A 280 bp sequence located -10 kb from the syndecan-1 translation initiation site functions as a promoter element for the syndecan-1 response to FGF-2. This 280 bp domain is termed the fibroblast growth factor-inducible response element. To date, similar elements have not been reported for syndecans 2 through 4.

Sexual Identity

The course of normal sexual development is also likely to be affected by a diagnosis of cancer during adolescence. The inherent lack of privacy that accompanies the illness is likely to inhibit or delay social exploration, while overprotective parents may limit the time spent away from the family. At the same time, there may be fewer peer contacts in the school environment and fewer opportunities for social exploration. Koocher et al. 41 , for example, found that adolescent girls with physical impairments had more difficulty establishing intimate relationships than similar girls without impairments. Concerns about late effects from the disease and treatment are superimposed on age-related issues such as establishing intimate relationships, defining physical attractiveness, and preparing for marriage and family 14 .

Limb training

The endurance training discussed above is mostly carried out using walking, treadmill, and cycling exercises. Strength training of the lower limbs is an attractive approach, because peripheral muscle weakness contributes to exercise limitation in patients with COPD 21,22 . Two studies have investigated this issue. Simpson et al. showed that specific strength training improved muscle function by 16-40 , depending on the specific muscle that was trained 23 . They also found an increased endurance capacity and an improved quality of life. Clark et al. showed that a programme of low-intensity leg and arm exercises leads to an improved walking distance and demonstrated a physiological training response by showing a reduced ventilatory equivalent for oxygen and carbon dioxide 24 .

Creatine

Creatine is an amin oacid derivative found in relatively large quantities in meat. It has been used in the last 10 years to improve exercise capacity in tasks that are brief but of high-intensity. Creatine acts to increase muscle phosphocreatine levels 105 and may increase the rate of phosphocreatine resynthesis 106 both of these effects result in improved, brief, high-intensity, intermittent exercise capacity 105 . Additionally, a combination of crea-tine ingestion and resistance exercise training has been shown to result in greater muscle-mass gains than resistance training alone in young individuals 107 . Creatine administration has been combined with resistance training in the elderly, with one investigation finding no effect 108 and others finding improvements in lean body mass and strength 109,110 . Thus, further investigation as to the potential anabolic actions of creatine and resistance training in older adults is warranted. There is one report of creatine supplementation...

Body Mass Index

Lean muscle mass, serum albumin levels, oxygen expenditure, hydrostatic weight measurement, potassium and water content. A statistically significant correlation of BMI and morbidity-mortality from all causes, diabetes, cardiovascular and infectious diseases, and cancer has been shown by unequivocal studies.

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