only with local administration
sarcoma, melanoma (isolated limb perfusion)
septic shock syndrome
In routine use to promote bone marrow recovery
GM-CSF, granulocyte-macrophage colony-stimulating factor; TNF, tumor necrosis factor.
expression on tumor cells, which makes them more susceptible to killing by CTLs (see Chapter 10). Other cytokines, such as TNF and IFN-y, are effective anti-tumor agents in animal models, but their use in patients is limited by serious toxic side effects. Hematopoietic growth factors, including GM-CSF and G-CSF are used in cancer treatment protocols to shorten periods of neutropenia and thrombocytopenia after chemotherapy or autologous bone marrow transplantation.
Was this article helpful?
All Natural Immune Boosters Proven To Fight Infection, Disease And More. Discover A Natural, Safe Effective Way To Boost Your Immune System Using Ingredients From Your Kitchen Cupboard. The only common sense, no holds barred guide to hit the market today no gimmicks, no pills, just old fashioned common sense remedies to cure colds, influenza, viral infections and more.