Tcr

receptor receptor receptor

Distribution of receptors

Nonclonal: identical receptors on all cells of the same lineage

Clonal: clones of lymphocytes with distinct specificities express different receptors

Discrimination of self Yes; healthy host cells are not recognized or they may and non-self express molecules that prevent innate immune reactions yes; based on elimination or inactivation of self-reactive lymphocytes; may be imperfect (giving rise to autoimmunity)

TABLE 4-2 Examples of PAMPs and DAMPs

Pathogen-Associated Molecular Patterns

Microbe Type

Nucleic acids

Virus, bacteria

Proteins

Pilin flagellin

Bacteria Bacteria

Cell wall lipids

Lipoteichoic acid

Gram-negative bacteria Gram-positive bacteria

Carbohydrates

Mannan Dectin glucans

Fungi, bacteria Fungi

Damage-Associated Molecular Patterns

Was this article helpful?

0 0
Dr. Atkins New Diet Revolution

Dr. Atkins New Diet Revolution

Wanting to lose weight and dont know where to start? Dr Atkins will help you out and lose weight fast. Learn more...

Get My Free Ebook


Post a comment