Selected Readings

Early B Cell Development and V(D)J Recombination

Cobaleda C, and M Busslinger. Developmental plasticity of lymphocytes. Current Opinion in Immunology 20:139-148, 2008.

Jenkinson EJ, WE Jenkinson, SW Rossi, and G Anderson. The thymus and T-cell commitment: the right choice for Notch? Nature Reviews Immunology 6:551-555, 2006.

Johnson K, KL Reddy, and H Singh. Molecular pathways and mechanisms regulating the recombination of immunoglobu-lin genes during B-lymphocyte development. Advances in Experimental Medicine and Biology 650:133-147, 2009.

Jung D, C Giallourakis, R Mostoslavsky, and FW Alt. Mechanism and control of V(D)J recombination at the immuno-globulin heavy chain locus. Annual Review of Immunology 24:541-570, 2006.

Nemazee D. Receptor editing in lymphocyte development and central tolerance. Nature Reviews Immunology 6:728-740, 2006.

Perlot T, and FW Alt. Cis-regulatory elements and epigenetic changes control genomic rearrangements of the IgH locus. Advances in Immunology 99:1-32, 2008.

Schatz DG, and Y JI. Recombination centers and the orchestration of V(D)J recombination. Nature Reviews Immunology vol. 11, March 2011.

T Cell Development

Boehm T. Thymus development and function. Current Opinion in Immunology 20:178-184, 2008.

Carpenter AC, and R Bosselut. Decision checkpoints in the thymus. Nature Immunology 11:666-673, 2010.

Godfrey DI, S Stankovic, and AG Baxter. Raising the NKT cell family. Nature Immunology 11:197-206, 2010.

He X, K Park, and DJ Kappes. The role of ThPOK in control of CD4/CD8 lineage commitment. Annual Review of Immunology 28:295-320, 2010.

Kyewski B, and L Klein. A central role for central tolerance. Annual Review of Immunology 24:571-606, 2006.

Maillard I, T Fang, and WS Pear. Regulation of lymphoid development, differentiation, and function by the Notch pathway. Annual Review of Immunology 23:945-974, 2005.

Rodewald HR. Thymus organogenesis. Annual Review of Immunology 26:355-388, 2008.

Rothenberg EV, JE Moore, and MA Yui. Launching the T-cell-lineage developmental programme. Nature Reviews Immunology 8:9-21, 2008.

Singer A, S Adoro, and JH Park. Lineage fate and intense debate: myths, models and mechanisms of CD4 versus CD8 lineage choice. Nature Reviews Immunology 8:788-801, 2008.

von Boehmer H, I Aifantis, F Gounari, O Azugui, L Haughn, I Apostolou, E Jaeckel, F Grassi, and L Klein. Thymic selection revisited: how essential is it? Immunological Reviews 191:6278, 2003.

MicroRNAs and Lymphocyte Development

Hoefig KP, and V Heissmeyer. MicroRNAs grow up in the immune system. Current Opinion in Immunology 20:281287, 2008.

Lodish HF, B Zhou, G Liu, and CZ Chen. Micromanagement of the immune system by microRNAs. Nature Reviews Immunology 8:120-130, 2008.

Xiao C, and K Rajewsky. MicroRNA control in the immune system: basic principles. Cell 136:26-36, 2009.

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