Irak

Ligands: IL-1, IL-18

Seven transmembrane G-protein-coupled receptors

G proteins

Ligands: Chemokines

Subunit composition of cytokine receptors

Common y chain family

GM-CSF receptor family (common ß chain)

IL-6 receptor family (common gp130 subunit)

gp130 gp130 gp130

ß

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