Info

Connective Tissue Mast Cells

Mucosal Mast Cells

Characteristic

Rodent

Human

Rodent

Human

Location

Peritoneal cavity

Skin, intestinal submucosa

Intestinal mucosa

Alveoli, intestinal mucosa

T cell dependence for development of phenotype in tissues

No

No

Yes

Yes

Granule contents

High levels of histamine, heparin

Major neutral proteases: tryptase, chymase, carboxypeptidase, cathepsin G

Low levels of histamine; high levels of chondroitin sulfate

Major neutral protease: tryptase

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