Info

Response to antigen

None

None

None

Negative selection (deletion), receptor editing

Activation (proliferation and differentiation)

FIGURE 8-14 Stages of B cell maturation. Events corresponding to each stage of B cell maturation from a bone marrow stem cell to a mature B lymphocyte are illustrated. Several surface markers in addition to those shown have been used to define distinct stages of B cell maturation.

FIGURE 8-14 Stages of B cell maturation. Events corresponding to each stage of B cell maturation from a bone marrow stem cell to a mature B lymphocyte are illustrated. Several surface markers in addition to those shown have been used to define distinct stages of B cell maturation.

I Heavy chain

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