TdT expression 1 1

Unrecombined Ig DNA, RNA (germline) DNA

Unrecombined (germline) DNA

Recombined H chain gene (VDJ); i mRNA

Recombined H chain gene (VDJ), k or X genes (VJ); i or k or X mRNA

Alternative splicing of VDJ-C RNA (primary transcript), to form C|x and C5 mRNA

Ig expression



Cytoplasmic i and pre-B receptor -associated i

Membrane IgM (i+ k or X light chain)

Membrane IgM and IgD

Surface markers


CD43+ CD19+ CD10+

B220lc CD43+

IgMlQ CD43-


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