In leukemia patients, administration of alloreactive T cells together with hematopoietic stem cell transplants can contribute to eradication of the tumor. This graft-versus-leukemia effect is directed at the allogeneic MHC molecules present on the recipient's hematopoietic cells, including the leukemia cells. The challenge in use of this treatment to improve clinical outcome is to minimize the dangerous graft-versus-host disease that may be mediated by the same donor T cells (see Chapter 16).
Was this article helpful?
Not Able To Lead A Happy Life Because Of Excessive Allergies? Want To Badly Get Rid Of Your Allergy Problems, But Are Super Confused And Not Sure Where To Even Start? Don't Worry, Help Is Just Around The Corner Revealed The All-In-One Power Packed Manual Containing Ample Strategies And Little-Known Tips To Get Rid Of Any Allergy Problems That Are Ruining Your Life Learn How You Can Eliminate Allergies Completely Reclaim Your Life Once Again