D1 J1

VM/C

N/P nucleotides

N/P nucleotides

N/P nucleotides

FIGURE 8-9 Diversity of antigen receptor genes. From the same germline DNA, it is possible to generate recombined DNA sequences and mRNAs that differ in their V-D-J junctions. In the example shown, three distinct antigen receptor mRNAs are produced from the same germline DNA by the use of different gene segments and the addition of nucleotides to the junctions.

N/P nucleotides

N/P nucleotides

N/P nucleotides

FIGURE 8-9 Diversity of antigen receptor genes. From the same germline DNA, it is possible to generate recombined DNA sequences and mRNAs that differ in their V-D-J junctions. In the example shown, three distinct antigen receptor mRNAs are produced from the same germline DNA by the use of different gene segments and the addition of nucleotides to the junctions.

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Heptamer CACAGTG GTGTCAC

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