The use of specialized blood products in patients with hematologic malignancies is an important part of the therapeutic and supportive care of these patients. While the indications for red cell transfusion are essentially the same for any patient who has anemia, platelets and other specialized components have unique requirements in this group of patients. The ready availability of leukocyte-reduced and/or irradiated blood components are essential elements for optimal patient care. Close cooperation and consultation between the treating physicians and the transfusion service are critical, as these patients can present many transfusion-related challenges. Transfusion medicine specialists should be readily available for consultation.

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