Like their B-cell counterparts, several types of T-cell and NK-cell lymphomas are currently recognized as distinct clinicopathologic entities. Importantly, approximately half of T-cell lymphomas do not appear to represent any of the currently defined clinicopatho-logic categories, and are instead classified as members of a heterogeneous group of lymphomas designated "peripheral T-cell lymphoma, unspecified" (see below). Establishing a diagnosis of a specific type of T-cell or NK-cell lymphoma is heavily dependent upon integration of the associated clinical data. Knowledge of the clinical findings is especially important for the cutaneous T-cell lymphomas. Close cooperation between the clinician and pathologist is therefore essential for the most precise diagnosis.
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