29. Besa E, Nowell P, Geller N, Gardner F: Analysis of the androgen response of 23 patients with agnogenic myeloid metaplasia: the value of chromosomal studies in predicting response and survival. Cancer 49:308, 1982.

30. Cervantes F, Hernandez-Boluda JC, Alvarez A, Nadal E, Montserrat E: Danazol treatment of idiopathic myelofi-brosis with severe anemia. Haematologica 85:595-599, 2000.

31. Levy V, Bourgarit A, Delmer A, et al.: Treatment of agnogenic myeloid metaplasia with danazol—a report of four cases. Am J Hematol 53:239-241, 1996.

32. Barosi G, Grossi A, Comotti B, Musto P, Gamba G, Marchetti M: Safety and efficacy of thalidomide in patients with myelofibrosis with myeloid metaplasia. Br J Haematol 114:78-83, 2001.

33. Canepa L, Ballerini F, Varaldo R, et al.: Thalidomide in agnogenic and secondary myelofibrosis. Br J Haematol 115:313-315, 2001.

34. Elliott MA, Mesa RA, Li CY, et al.: Thalidomide treatment in myelofibrosis with myeloid metaplasia. Br J Haematol 117:288-296, 2002.

35. Grossi A, Gavazzi S, Biscardi M, et al.: Thalidomide therapy effects on angiogenic growth factors (VEGF, TGF-Beta) and KDR expression in myeloid metaplasia with myelofibrosis. Blood 100:a4939, 2002.

36. Marchetti M, Barosi G, Balestri F, et al.: Low-dose thalidomide ameliorates cytopenias and splenomegaly in myelofibrosis with myeloid metaplasia: a phase II trial. J Clin Oncol 22:424-431, 2004.

37. Merup M, Kutti J, Birgergard G, et al.: Negligible clinical effects of thalidomide in patients with myelofibro-sis with myeloid metaplasia. Med Oncol 19:79-86, 2002.

38. Piccaluga PP, Visani G, Pileri SA, et al.: Clinical efficacy and antiangiogenic activity of thalidomide in myelofi-brosis with myeloid metaplasia. A pilot study. Leukemia 16:1609-1614, 2002.

39. Pozzato G, Zorat F, Nascimben F, Comar C, Kikic F, Festini G: Thalidomide therapy in compensated and decompensated myelofibrosis with myeloid metaplasia. Haematologica 86:772-773, 2001.

40. Strupp C, Germing U, Scherer A, et al.: Thalidomide for the treatment of idiopathic myelofibrosis. Eur J Haematol 72:52-57, 2004.

41. Mesa RA, Steensma DP, Pardanani A, et al.: A phase 2 trial of combination low-dose thalidomide and pred-nisone for the treatment of myelofibrosis with myeloid metaplasia. Blood 101:2534-2541, 2003.

42. Visani G, Mele A, Malagola M, Isidori A, Finelli C, Piccaluga P: Sequential combination of thalidomide and erythropoietin determines transfusion independence and disease control in idiopathic myelofibrosis previously insensitive to both drugs as single agents. Leukemia 17:1669, 2003.

43. Tefferi A, Elliott MA: Serious myeloproliferative reactions associated with the use of thalidomide in myelofibrosis with myeloid metaplasia. Blood 96:4007, 2002.

44. Kyrtsonis MC, Kokoris SI, Kontopidou FN, Siakantaris MP, Kittas C, Pangalis GA: Development of a myelopro-liferative disorder in a patient with monoclonal gam-mopathy of undetermined significance secreting immunoglobulin of the M class and treated with thalidomide and anti-CD20 monoclonal antibody. Blood 97:2527-2528, 2001.

45. Mesa RA, Elliott MA, Faoro L, Tefferi A: Durable and unmaintained remissions with thalidomide-based drug therapy in myelofibrosis with myeloid metaplasia: long term outcome analysis of 2 prospective trials. Blood 102:a104, 2003.

46. Jensen M: Splenectomy in myelofibrosis. Acta Med Scand 175:533-544, 1964.

47. Hickling RA: Splenectomy in myeloid metaplasia. QJ Med 30:253, 1937.

48. Bukh H, With TK: Splenectomy in chronic non-leukemic myeloid splenomegaly with a report of osteosclerosis. Acta Chir Scand 92:507-532, 1945.

49. Green TW, Conley C, Ashburn LI, Peters HR: Splenectomy for myeloid metaplasia of the spleen. N Engl J Med 248:211-219, 1953.

50. Videbaek A: Fibrosis and sclerosis of the bone marrow. Acta Haematol 15:235-245, 1956.

51. Gomes MR, Silverstein MN, Remine WH: Splenectomy for agnogenic myeloid metaplasia. Surg Gynecol Obstet 125:106-108, 1967.

52. Schwartz SI, Bernard RP, Adams JT, Bauman AW: Splenectomy for hematologic disorders. Arch Surg 101:338-347, 1970.

53. Morgenstern L: Splenectomy for massive splenomegaly due to myeloid metaplasia. Am J Surg 122:288-293, 1971.

54. Milner GR, Geary CG, Wadsworth LD, Doss A: Erythrokinetic studies as a guide to the value of splenectomy in primary myeloid metaplasia. Br J Haematol 25:467-484, 1973.

55. Silverstein MN, Remine WH: Sex, splenectomy, and myeloid metaplasia. JAMA 227:424-426, 1974.

56. Gale D, Sacks P, Lynch S, Bothwell TH, Bezwoda W, Stevens K: The place of splenectomy in haematological disorders. S Afr Med J 48:1240-1245, 1974.

57. Mulder H, Steenbergen J, Haanen C: Clinical course and survival after elective splenectomy in 19 patients with primary myelofibrosis. Br J Haematol 35:419-427, 1977.

58. Cabot EB, Brennan MF, Rosenthal DS, Wilson RE: Splenectomy in myeloid metaplasia. Ann Surg 187:24-30, 1978.

59. Little JM: A prospective study of 100 splenectomies. AustN Z J Surg 48:390-397, 1978.

60. Silverstein MN, Remine WH: Splenectomy in myeloid metaplasia. Blood 53:515-518, 1979.

61. Benbassat J PS, Ligumski M: Splenectomy in patients with agnogenic myeloid metaplasia: an analysis of 321 published cases. Br J Haematol 42:207-214, 1979.

62. Jarvinen H, Kivilaakso E, Ikkala E, Vuopio P, Hastbacka J: Splenectomy for myelofibrosis. Ann Clin Res 14:66-71, 1982.

63. Coon WW, Liepman MK: Splenectomy for agnogenic myeloid metaplasia. Surg Gynecol Obstet 154:561-563, 1982.

64. Musser G, Lazar G, Hocking W, Busuttl W: Splenectomy for hematologic disease. Ann Surg 200:40-45, 1984.

65. Sharp P, Grace CS, Rozenberg MC, Ham JM: Splenectomy for massive splenomegaly. Aust N Z J Surg 55:489-492, 1985.

66. Dotevall A, Kutti J, Wadenvik H, Westin J: A retrospective analysis of a consecutive series of patients splenec-tomized for various hematologic disorders. Acta Haematol 77:38-44, 1987.

67. Benbassat J, Gilon D, Penchas S: The choice between splenectomy and medical treatment in patients with advanced agnogenic myeloid metaplasia. Am J Hematol 33:128-135, 1990.

68. Brenner B, Nagler A, Tatarsky I, Hashmonai M: Splenectomy in agnogenic myeloid metaplasia and postpolycythemic myeloid metaplasia. A study of 34 cases. Arch Intern Med 148:2501-2505, 1988.

69. Schmitz N, Suttorp M, Schlegelberger B, Weber-Matthiesen K, Tiemann M, Sonnen R: The role of the spleen after bone marrow transplantation for primary myelofibrosis. Br J Haematol 81:616-618, 1992.

70. Barosi G, Ambrosetti A, Buratti A, et al.: Splenectomy for patients with myelofibrosis with myeloid metaplasia: pretreatment variables and outcome prediction. Leukemia 7:200-206, 1993.

71. Lafaye F, Rain JD, Clot P, Najean Y: Risks and benefits of splenectomy in myelofibrosis: an analysis of 39 cases. Nouv Rev Fr Hematol 36:359-362, 1994.

72. Jameson JS, Thomas WM, Dawson S: Splenectomy for haematologic disease. J R Coll Surg Edinb 41:307-311, 1996.

73. Mittelman MKS, Zeidman A: Splenectomy for hematologic disease—a single institution experience. Haematologica 28:185-198, 1997.

74. Bohner H, Tirier C, Rotzcher VM: Indications for and results of splenectomy in different hematologic disorders. Langenbecks Arch Chir 382:79-82, 1997.

75. Barosi G, Ambrosetti A, Centra A, et al.: Splenectomy and risk of blast transformation in myelofibrosis with myeloid metaplasia. Italian Cooperative Study Group on Myeloid with Myeloid Metaplasia. Blood 91:3630-3636, 1998.

76. Akpek G, McAneny D, Weintraub L: Risks and benefits of splenectomy in myelofibrosis with myeloid metaplasia: a retrospective analysis of 26 cases. J Surg Oncol 77:42-48, 2001.

77. Lofvenberg E, Wahlin A: Management of poly-cythaemia vera, essential thrombocythaemia and myelofibrosis with hydroxyurea. Eur J Haematol 41:375-381, 1988.

78. Best PJ, Daoud MS, Pittelkow MR, Petitt RM: Hydroxyurea-induced leg ulceration in 14 patients [see comments]. Ann Intern Med 128:29-32, 1998.

79. Manoharan A, Pitney WR: Chemotherapy resolves symptoms and reverses marrow fibrosis in myelofibro-sis. Scand J Haematol 33:453-459, 1984.

80. Petti MC, Latagliata R, Spadea T, et al.: Melphalan treatment in patients with myelofibrosis with myeloid metaplasia. Br J Haematol 116:576-581, 2002.

81. Tefferi A, Silverstein MN, Li CY: 2-Chlorodeoxyadenosine treatment after splenectomy in patients who have myelofibrosis with myeloid metaplasia. Br J Haematol 99:352-357, 1997.

82. Mesa RA, Camoriano JK, Geyer SM, et al.: A phase 2 consortium (P2C) trial of R115777 (Zarnestra) in myelofibrosis with myeloid metaplasia: interim analysis of 18 patients. Blood 102:a3428, 2003.

83. Giles FJ, List AF, Roboz GJ, et al.: Phase I/II study of PTK787/ZK 222584 (PTK/ZK), a novel, oral VEGF-recep-tor inhibitor, in patients with myelofibrosis with myeloid metaplasia. Blood 102:a3431, 2003.

84. Silverstein MN: Control of hypersplenism and painful splenomegaly in myeloid metaplasia by irradiation. Int J Radiat Oncol Biol Phys 2:1221-1222, 1977.

85. Greenberger JS, Chaffey JT, Rosenthal DS, Moloney WC: Irradiation for control of hypersplenism and painful splenomegaly in myeloid metaplasia. Int J Radiat Oncol Biol Phys 2:1083-1090, 1977.

86. Slanina J, Vondraczek A, Wannenmacher M: Symptomatic irradiation therapy of the spleen in advanced osteomyelosclerosis. Dtsch Med Wochenschr 111:1144-1150, 1986.

87. Wagner H Jr, McKeough PG, Desforges J, Madoc-Jones H: Splenic irradiation in the treatment of patients with chronic myelogenous leukemia or myelofibrosis with myeloid metaplasia. Results of daily and intermittent fractionation with and without concomitant hydroxyurea. Cancer 58:1204-1207, 1986.

88. Elliott MA, Chen MG, Silverstein MN, Tefferi A: Splenic irradiation for symptomatic splenomegaly associated with myelofibrosis with myeloid metaplasia. Br J Haematol 103:505-511, 1998.

89. Bouabdallah R, Coso D, Gonzague-Casabianca L, Alzieu C, Resbeut M, Gastaut JA: Safety and efficacy of splenic irradiation in the treatment of patients with idiopathic myelofibrosis: a report on 15 patients. Leuk Res 24:491-495, 2000.

90. McFarland JT, Kuzma C, Millard FE, Johnstone PA: Palliative irradiation of the spleen. Am J Clin Oncol 26:178-183, 2003.

91. Tefferi A, Jimenez T, Gray LA, Mesa RA, Chen MG: Radiation therapy for symptomatic hepatomegaly in myelofibrosis with myeloid metaplasia. Eur J Haematol 66:37-42, 2001.

92. Leinweber C, Order SE, Calkins AR: Whole-abdominal irradiation for the management of gastrointestinal and abdominal manifestations of agnogenic myeloid metaplasia. Cancer 68:1251-1254, 1991.

93. Koch C, Li C, Mesa R, Tefferi A: Nonhepatosplenic extrameduallry hematopoiesis: associated diseases, pathology, clinical course, and treatment. Mayo Clin Proc 78:1223-1233, 2003.

94. Steensma DP, Hook CC, Stafford SL, Tefferi A: Low-dose, single-fraction, whole-lung radiotherapy for pulmonary hypertension associated with myelofibrosis with myeloid metaplasia. Br J Haematol 118:813-816, 2002.

95. Weinschenker P, Kutner JM, Salvajoli JV, et al.: Whole-pulmonary low-dose radiation therapy in agnogenic myeloid metaplasia with diffuse lung involvement. Am JHematol 69:277-280, 2002.

96. Battegay EJ, Raines EW, Colbert T, Ross R: TNF-alpha stimulation of fibroblast proliferation. Dependence on platelet-derived growth factor (PDGF) secretion and alteration of PDGF receptor expression. J Immunol 154:6040-6047, 1995.

97. Rusten LS, Jacobsen SE: Tumor necrosis factor (TNF)-alpha directly inhibits human erythropoiesis in vitro: role of p55 and p75 TNF receptors. Blood 85:989-996, 1995.

98. Dinarello CA, Cannon JG, Wolff SM, et al.: Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1. J Exp Med 163:1433-1450, 1986.

99. Steensma DP, Mesa RA, Li CY, Gray L, Tefferi A: Etanercept, a soluble tumor necrosis factor receptor, palliates constitutional symptoms in patients with myelofibrosis with myeloid metaplasia: results of a pilot study. Blood 99:2252-2254, 2002.

100. Cervantes F, Tassies D, Salgado C, Rovira M, Pereira A, Rozman C: Acute transformation in nonleukemic chronic myeloproliferative disorders: actuarial probability and main characteristics in a series of 218 patients. Acta Haematol 85:124-127, 1991.

101. Mesa RA, Tefferi A: Survival and outcomes to therapy in leukemic transformation of myelofibrosis with myeloid metaplasia: a single institution experience with 91 patients. Blood 102:a3414, 2003.

Chapter 50

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