Denton Farris, a former businessman, developed urinary protein and red cells at age 65. Blood tests showed that he had a kind of kidney disease called IgA nephropathy but only mild loss of kidney function. Because of recurrent muscle pains caused by a rare disorder called polymyalgia, he was taking 5 mg per day of prednisone. An ACE inhibitor was prescribed for hypertension, which necessitated the addition of sodium polystyrene sulfonate to prevent high blood potassium concentration. As his renal function declined, a very-low-protein diet was added, supplemented alternately by amino acids or ketoacids. Later, additional antihypertensive drugs and diuretics were also added. He took ketoconazole intermittently, with uncertain effects on progression. Erythropoietin injections were added. Finally, at age 74, he went on dialysis and died a year later, after withdrawing from dialysis.
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