General Management

Ipecac is contraindicated due to excessive vomiting-induced risk of preterm labor. Coma cocktails should contain dextrose and naloxone.

Activated charcoal (AC) is very useful because of gastric axis shift with gastric content stasis. Whole-bowel irrigation (WBI) with polyethylene glycol-electrolyte solution (PEG-ELS) is indicated for iron (Fe) overdose to flush out slow-release tablets; Fe is not AC-adsorbed. Most antidotes are FDA category C or better; only ethanol is category D. Never withhold specific antidotes in pregnancy, especially NAC for acetaminophen (APAP) overdose, a commonly ingested suicidal agent.

Increased dermal absorption: Hexachloro-phene-vacuolar encephalopathy, aniline dyes may cause methemoglobenemia (MetHb), iodine-containing antiseptics may cause hypothyroidism.

Increased protein binding: Sulfonamides and ceftriaxone displace bilirubin from albumin and cause kernicterus in neonates. Reduced hepatic P-450 metabolism: High concentrations of phenytoin, phenobarbital, theophylline cause reduced glucuronidation of chloramphenicol with resulting gray baby syndrome; benzyl alcohol = gasping baby syndrome.

General management: No ipecac or lavage due to existing electrolyte and temperature losses; consider exchange transfusion > hemodialysis > hemoperfusion for drug overdoses.

Dealing With Asthma Naturally

Dealing With Asthma Naturally

Do You Suffer From ASTHMA Chronic asthma is a paralyzing, suffocating and socially isolating condition that can cause anxiety that can trigger even more attacks. Before you know it you are caught in a vicious cycle Put an end to the dependence on inhalers, buying expensive prescription drugs and avoidance of allergenic situations and animals. Get control of your life again and Deal With Asthma Naturally

Get My Free Ebook


Post a comment