Delayed Manifestations

CNS neurotoxicity predominates: Confined to basal ganglia = globus pallidus, putamen, hippocampus (CT confirmation) resulting in toxic parkinsonism, with bradykinesia, dystonia, dysarthria, no rigidity (L-dopa resistant). Chronic low-level cyanide toxicity occurs in: (1) Tobacco amblyopia (male smokers); (2) tropical (cassava root) ataxic neuropathy, (3) Leber's hereditary optic atrophy (males). Mechanism: low endogenous stores of CN-detoxify-ing hydroxocobalamin and thiosulfate. Results from depletion of detoxifying substances by chronic low-grade CN poisoning from cigarette smoking (tobacco amblyopia and Leber's heredity optic atrophy) or frequent cassava root ingestion (tropical ataxic neuropathy).

Cigarette Crusher

Cigarette Crusher

Get All The Support And Guidance You Need To Permanently STOP Being A Slave To Nicotine And Cigarettes. This Book Is One Of The Most Valuable Resources In The World When It Comes To Easy Ways To Eliminate Smoking Addiction And Revitalize Your Body.

Get My Free Ebook


Post a comment