Introduction

The European Bioinformatics Institute (EBI) is a major center for biological data. Research groups have collected genome-related data for the last 15 years, during which the amount of data has grown exponentially. There are now more than 300 publicly available collections of highly interrelated data. The more the size and complexity of molecular biology data grow, the more important become automatic tools for management, querying and analysis. The current limitations in using this wealth of...

Voxel Models and Database Structure

Database systems for spatially mapped information have been developed and in long use as Geographic Information Systems and a number are now emerging for biomedical research and teaching 9,10,11,12 . The special feature of biomedical atlases is that there is no single correct object, i.e. the underlying structures show natural variation and the processing steps to acquire the data introduces additional systematic and random spatial variation. This raises additional problems of data mapping in...