Sources of further information and advice 691 Further reading for modelling migrants

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Brandsch J., Mercea P., Ruter M., Tosa V., Piringer O. (2002), Migration modelling as a tool for quality assurance of food packaging, Food Additives and Contaminants, 19, pp 29-41.

O'Brien A., Cooper I., (2002), Practical experience in the use of additive models to predict migration of additives from food contact polymers, Food Additives and Contaminants, 19, pp 56-62.

Reynier A., Dole P., Feigenbaum A., (2002), Integrated approach of migration prediction using numerical modelling associated to determination of key parameters, Food Additives and Contaminants, 19, pp 42-55.

6.9.2 Further reading for the threshold of toxicological concern

Barlow S, (2005), Threshold of toxicological concern (TTC) a tool for assessing substances of unknown toxicity present in the diet, ILSI Monograph 2005.

Cheeseman M.A., Machuga E.J., Bailey E.B., (1999), A tiered approach to threshold of regulation, Food and Chemical Toxicology 37, pp 387-412.

Cramer C.M., Ford R.A., Hall R.L., (1967) Estimation of a toxic hazard - a decision tree approach. Food and Cosmetics Toxicology 5, pp 293-308.

ILSI Monograph, (2000), Threshold of toxicological concern for chemical substances present in the diet, August 2000.

Kroes R., Galli C., Munro I., Schilter B., Tran L.-A., Walker R., Wurtzen G., (2000), Threshold of toxicological concern for chemical substances present in the diet: a practical tool for assessing the need for toxicity testing. Food and Chemical Toxicology 38, pp 255-312.

Kroes R., Renwick A.G., Cheeseman M., Kleiner J., Mangelsdorf I., Piersma A., Schilter B., Schlatter J., van Schothorst F., Vos J.G., Wurtzen G., (2004), Structure based thresholds of toxicological concern (TTC): Guidance for application to substances present at low levels in the diet. Food and Chemical Toxicology 42, pp 65-83.

Munro I.C., Ford R.A., Kennepohl E., Sprenger J.G., (1996), Correlation of a structural class with no-observed-effect levels: a proposal for establishing a threshold of concern. Food and Chemical Toxicology 34, pp 829-867.

US Food and Drug Administration. Food additives: Threshold of regulation for substances used in food contact articles; final rule. Federal Register 60, 36582-36596, Monday July 17, 1995.

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