Chronic intraocular inflammation, such as anterior, intermediate or posterior uveitis, can be complicated by disc swelling. Severe diabetic eye disease can sometimes be marked by disc swelling (diabetic papillopathy). In severe cases of thyroid orbitopathy, the orbital congestion
can cause disc swelling (dysthyroid optic neuropathy). In both instances, the doctor should be warned that serious consequences might ensue unless prompt treatment is applied. Infiltration of the disc by leukaemia, lymphoma or chronic granulomata (as in sarcoidosis) can also cause disc swelling.
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