Endophthalmitis and Panophthalmitis

When inflammatory changes in the posterior uvea extend into the vitreous and there is an extensive involvement of the centre of the globe, the patient is said to have endophthalmitis. Further extension of the inflammation into the anterior segment of the eye and into the sclera leads to panophthalmitis. Endophthalmitis is one of the feared results of infection after injury or surgery but it can prove reversible with intensive antibiotic treatment. When endophthal-mitis and panophthalmitis are not properly and aggressively treated, the sight is usually lost permanently and after months or years the whole eye begins to shrink.

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