Beh$et's disease is a multisystem disease associated with HLA-B5. It was originally thought to occur only in the Mediterranean and Japan, where it is most common. It is characterised by an obliterative vasculitis. The clinical syndrome consists of oral and genital ulceration in combination with recurrent uveitis and skin lesions. The uveitis consists of recurrent bilateral non-granulomatous anterior and/or posterior uveitis. Central nervous system involvement occurs as a serious form of the disease.
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