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Biographies

Rheem A Totah obtained a PhD in Medicinal Chemistry in 2002 from the University of Kansas. Later, she spent 18 months as an Elmer M and Joy B Plein Fellow for Excellence in Pharmacy Education at the University of Washington. Currently Dr Totah is an Acting Assistant Professor in the Medicinal Chemistry Department at the University of Washington. Dr Totah's research interests are focused on studying the mechanism and structure-activity relationship of cytochrome P450 enzymes especially those expressed mainly in extrahepatic tissues.

Allan E Rettie obtained a PhD in Pharmaceutical Sciences following studies at the Wolfson Unit at the University of Newcastle-upon-Tyne, England under the direction of Prof Sir Michael Rawlins. After postdoctoral research training with Drs Mont Juchau and William Trager at the University of Washington, Seattle, Dr Rettie joined the faculty of the School of Pharmacy at the same institution, where he is now Professor and Chair of Medicinal Chemistry. Dr Rettie's research interests revolve around structure-function relationships for the cytochrome P450 enzymes, particularly those in the CYP2 and CYP4 families, and the pharmacogenomics of oral anticoagulants.

© 2007 Elsevier Ltd. All Rights Reserved Comprehensive Medicinal Chemistry II

No part of this publication may be reproduced, stored in any retrieval system or transmitted ISBN (set): 0-08-044513-6 in any form by any means electronic, electrostatic, magnetic tape, mechanical, photocopying, recording or otherwise, without permission in writing from the publishers ISBN (Volume 5) 0-08-044518-7; pp. 167-191

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