Pityriasis Rubra Pilaris

Clinical Presentation (Fig. 5A):

■ Adult and juvenile forms

■ Diffuse and coalescing scaly plaques on trunk and extremities

■ Salmon-pink colored lesions

■ Follicular accentuation with perifollicular erythema

■ Islands of spared skin

■ Palmoplantar keratoderma

Histology (Fig. 5B):

■ Mild psoriasiform epidermal hyperplasia

■ Thickened suprapapillary epidermal plates

■ Stratum corneum with vertical and horizontally oriented alternating ortho and parakeratosis in a "checker board" pattern

■ Hyperkeratotic plugged follicular infundibuli

Table 2B Histologic Differential Diagnosis: Inflammatory Linear Verrucous Epidermal Nevus

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