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Intraepidermal and infundibular

Intraepidermal and infundibular

pustules often

pustules often

Mixed infiltrate containing

Mixed infiltrate containing

neutrophils

neutrophils

Pathophysiology:

■ Erythrasma is caused by Corynebacterium minutissimum, a porphyrin-producing diphtheroid bacillus.

References:

1. Montes LF, Black SH, McBride ME. Bacterial invasion of the stratum corneum in erythrasma. I. Ultrastructural evidence for a keratolytic action exerted by Corynebacterium minutissimum. J Invest Dermatol 1967; 49:474-485.

2. Sindhuphak W, MacDonald E, Smith EB. Erythrasma. Overlooked or misdiagnosed? Int J Dermatol 1985; 24:95-96.

Acknowledgments:

Parts of the text of this chapter are extracted with permission from Chapter 10: Inflammatory Diseases. In: Ackerman AB, Boer A, Bennin B, Gottlieb GJ. Histologic Diagnosis of Inflammatory Skin Diseases, 3rd ed. New York: Ardor Scribendi, 2005; available at www.derm101.com.

Photomicrographs 1B and 1C and 7 to 14B and 14C are reproduced with permission from Ackerman AB, Boer A, Bennin B, Gottlieb GJ. Histologic Diagnosis of Inflammatory Skin Diseases, 3rd ed. New York: Ardor Scribendi, 2005; available at www.derm101.com.

Photomicrographs 2B and 2C, 6B and 6C are reproduced with permission from Ackerman AB. Interactive Quizzes: CPC. New York: Ardor Scribendi, 2005; available at www.derm101.com.

Clinical Feature

Pathologic Feature

Red macules, patches, and

Sparse superficial perivascular infiltrate

subtle plaques

of lymphocyte

Scale

Orthokeratosis which houses

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