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histiocytes

Figure 1 Multinucleated giant cells.

(A) Langhan's multinucleated giant cell.

(B) Touton multinucleated giant cell.

(C) Foreign body multinucleated giant cell. (D) Asteroid body in a multinucleated giant cell.

Figure 1 Multinucleated giant cells.

(A) Langhan's multinucleated giant cell.

(B) Touton multinucleated giant cell.

(C) Foreign body multinucleated giant cell. (D) Asteroid body in a multinucleated giant cell.

Figure 2 Granulomas. (A) Tuberculoid granuloma. (B) Sarcoidal granuloma. (C) Palisaded granuloma. (D) Caseation necrosis within a granuloma.

Figure 3 Lupus vulgaris. (A) Reddish brown plaque. (B) and (C) Nodular tuberculoid granulomas. (D) Caseation necrosis.

Figure 4 Tuberculoid leprosy. (A) Hypopipmented plaques. (B) Nodular elliptical tuberculoid granulomas. (C) and (D) Granulomas around hair erector muscle. (E) Tuberculoid granuloma. (F) and (G) Granulomas around small nerves.

Figure 4 Tuberculoid leprosy. (A) Hypopipmented plaques. (B) Nodular elliptical tuberculoid granulomas. (C) and (D) Granulomas around hair erector muscle. (E) Tuberculoid granuloma. (F) and (G) Granulomas around small nerves.

Focal swelling within a tattoo. (B) Allergic Figure 7 Sarcoid. (A) Lupus pernio, red nodule on nose. (B-D) Round sarcoidal granulomas. sarcoidal granulomas containing tattoo (E) Fibrin within a tubercle. granules that appear histologically black.

Figure 9 Cheilitis granulomatosa. (A) Enlargement of lower lip. (B) Sarcoidal granulomas within mucosal skin.

Figure 10 Granuloma annulare. (A) Pink papules annularly arranged. (B) and (C) Palisaded granulomas with mucin in the center. (D) colloidal iron stain highlighting increased mucin.

Figure 11 Necrobiosis lipoidica. (A) Yellowish atrophic plaque with telangiectasia on the skin. (B) Entire specimen with tiers of nodular palisaded granulomas. (C) Palisaded granuloma around degenerated collagen. (D) Telangiectasias with surrounding plasma cells.

Figure 13 Gout. (A) White chalky papule on toes. (B) and (C) Palisaded granulomas around amorphous feathery basophilic matrix.

Figure 12 Rheumatoid nodule. (A) Skin colored nodule. (B) Subcutaneous palisaded granuloma with central fibrin.

Figure 13 Gout. (A) White chalky papule on toes. (B) and (C) Palisaded granulomas around amorphous feathery basophilic matrix.

Figure 14 Necrobiotic xanthogranuloma. (A) Yellowish plaques periorbitally. (B) and (C) Extensive palisading granulomas in intersecting bands with extensive necrobioisis. (D) Touton giant cells.

Figure 17 Calcinosis cutis. (A) Whitish papules. (B) Foreign body granulomatous reaction around blue staining calcium within the dermis.

Figure 18 Lichen nitidus. (A) Tiny papules. (B) and (C) Histiocytes in the widened dermal papillae beneath which is a band of lymphocytes and around which the rete ridges form a "ball-and-claw" appearance.

Figure 19 Aspergillosis. (A) Nodules at site of an intravenous line in an immunosuppressed patient. (B) and (C) Suppurative granulomatous nodular infiltrate. (D) GMS stain demonstrating branching hyphae.

Figure 20 Bromoderma. (A) Papulo-nodules on the leg. (B) Ruptured follicle with a nodular suppurative and granulomatous infiltrate. (C) and (D) Suppurataive and granulomatous nodule.

Figure 22 Xanthogranuloma. (A) Yellow tan Figure 21 Xanthoma. (A) Yellowish papules. (B) nodules. (B) and (C) Diffuse infiltrate of foam and (C) Diffuse infiltrate of foam cells. cells and Touton giant cells.

Figure 22 Xanthogranuloma. (A) Yellow tan Figure 21 Xanthoma. (A) Yellowish papules. (B) nodules. (B) and (C) Diffuse infiltrate of foam and (C) Diffuse infiltrate of foam cells. cells and Touton giant cells.

Figure 24 Lepromatous leprosy. (A) Nodules on the face. (B) and (C) Diffuse infiltrate of histiocytes with gray cytoplasm. (D) and (E) Small nerves surrounded by infiltrate. (F) Fite stain demonstrating acid-fast organisms.

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