Persistent Pigmented Purpuric
Perivascular or lichenoid infiltrate
Eosinophils in the infiltrate
Vacuolar alteration and necrotic keratinocytes often
No changes of collagen
Perivascular and interstitial, sometimes lichenoid, infiltrate
Lymphocytes, erythrocytes, and siderophages
No changes in the epidermis or slight spongiosis
Wiry bundles of collagen
■ Erythema infectiosum is caused by parvovirus B19, roseola is caused by human herpesvirus 6, and other exanthems are caused by other specific viruses.
1. Ackerman AB, Boer A, Bennin B, Gottlieb GJ. Histologic Diagnosis of Inflammatory Skin Diseases. 3rd ed. New York: Ardor Scribendi, 2005.
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