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■ Hyperplastic epidermis with spongiosis (Fig. 13B)

■ Lymphocytes extend into the epidermis (Fig. 13B)

■ There may be mild hyperkeratosis or focal parakeratosis

Pathophysiology:

■ Etiology of lichen striatus is unknown

■ Suppressor-cytotoxic CD8+ T lymphocytes effect a cell-mediated cytotoxic immune reaction against kerati-nocytes

References:

1. Taieb A, el Youbi A, Grosshans E, Maleville J. Lichen striatus. A Blaschko linear acquired inflammatory skin eruption. J Am Acad Dermatol 1991; 25(4):637-642.

2. Gianotti R, Restano L, Grimalt R, et al. Lichen striatus—a chameleon: an histopathological and immunohistological study of forty-one cases. J Cutan Pathol 1995; 22(1):18-22.

3. Tosti A, Peluso AM, Misciali C, Cameli N. Nail lichen striatus: clinical features and long-term follow-up of five patients. J Am Acad Dermatol 1997; 36(6 Pt 1):908-913.

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