Epidermolysis Bullosa Simplex

Synonyms: Koebner [generalized form of epidermolysis bullosa simplex (EBS)]; Weber-Cockayne (localized form of EBS).

Clinical Presentation (Fig. 12A): Koebner (Generalized Form of EBS):

■ Occurs at birth or shortly thereafter; may improve with time

■ Vesicles, bullae, and milia over the joints of the hands, elbows, knees, feet, and other sites subject to repeated trauma

■ Lesions are sparse and do not lead to atrophy or severe scarring

■ Worse during summer; improves during winter

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