Rare And Unusual Cysts

These lesions are cystic and clinically recognized only by their unusual locations. The diagnoses depend on multiple specific criteria with the type of epithelial lining being most important. Clinical Presentation and Histology Pigmented Follicular Cyst Brown cystic lesion, face and neck, may resemble other pigmented neoplasms, usually solitary Epithelial lining similar to normal epidermis of the infundibulum of a hair follicle Amorphous pigmented keratin in cavity, with or without portions of...

Follicular Diseases Causing Scarring Alopecia

Follicular destruction results in scarring alopecia that can be classified as primary or secondary. In primary scarring alopecias, the follicle is the target of inflammation. In secondary scarring alopecias, the follicle is an innocent bystander that, nevertheless, is destroyed. Examples of secondary scarring alopecias include morphea and tumors (alopecia neoplastica). In this chapter, we will consider only the primary scarring alopecias. In this group of diseases, the inflammation can be...

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Figure 1 Multinucleated giant cells. (A) Langhan's multinucleated giant cell. (B) Touton multinucleated giant cell. (C) Foreign body multinucleated giant cell. (D) Asteroid body in a multinucleated giant cell. Figure 1 Multinucleated giant cells. (A) Langhan's multinucleated giant cell. (B) Touton multinucleated giant cell. (C) Foreign body multinucleated giant cell. (D) Asteroid body in a multinucleated giant cell. Figure 2 Granulomas. (A) Tuberculoid granuloma. (B) Sarcoidal granuloma. (C)...

Basal Cell Carcinoma

Occurs in sites chronically exposed to the sun and increased in frequency from the third decade onward, although they have been reported in children and young adults. Most frequently on the face and scalp, rarely arises on the digits, the back of the hand, dorsum of the foot, or on the ears. Typically are solitary opalescent nodules with telangiectasia (Fig. 18A) or ulceration (Fig. 18B). Common variant is the superficial type (Fig. 18C), which often appears as a thin plaque. Morphea-form may...

Digital Myxoid Cyst

Most common on the dorsal surface of the index or middle finger, overlying the distal interphalangeal joint, just above the proximal nail fold (Fig. 20C) Ill-defined collection of mucin in superficial dermis, may have overlying collarette of epidermis (Fig. 20D) Mild inflammation at the periphery Figure 1 (A) Multiple well circumscribed, hyperplgmented, verrucous plaques with a stuck-on appearance. (B) Well circumscribed and symmetric lesion demonstrating papillomatosis and acanthosis of the...

Rl81a85434 2007

Visit the Informa Web site at www.informa.com and the Informa Healthcare Web site at www.informahealthcare.com This book is dedicated to the memory of my Dad, George H. Grant, D.D.S. who died on June 8, 2006 at noon and to my husband, Barry D. Kels, M.D., J.D. They are both gentle yet strong, demonstrate an absolute love of life and family, and my greatest supporters. In their arms, I have learned what it means to feel safe and secure. My Dad was the first man in my life that I loved with every...

Combined Nevus

Combined nevus is a variant of benign melanocytic neoplasm characterized by the presence of two or more distinct populations of melanocytes Table 21 Fig. 14 . Virtually, any combination of melanocytic components may occur, for example, common acquired nevus and common blue nevus, common nevus and pigmented spindle cell epithelioid cell dermal component Figs. 14B-D , Spitz and blue nevus components, congenital nevus and blue nevus and so on. Synonym Melanocytic nevus with phenotypic...

References

Clark WH Jr, Elder DE, Guerry D IV, et al. A study of tumor progression the precursor lesions of superficial spreading and nodular melanoma. Human Pathol 1984 15 1147-1165. 2. Elder DE. The dysplastic nevus. Pathology 1985 17 291-297. 3. Barnhill RL, Roush GC, Duray PH. Correlation of histologic and cytoplasmic features with nuclear atypia in atypical dysplastic nevomelanocytic nevi. Hum Pathol 1990 21 51-58. 4. Piepkorn MW. An appraisal of the dysplastic nevus syndrome concept. Adv Dermatol...

Clinical Evolution of Melanoma

Malignant melanomas may arise de novo, that is, in apparently normal skin or in association with a pre-existing melanocytic nevus. When malignant melanomas arise de novo, they begin as a small, lightly pigmented macule that in time is characterized by asymmetry, scalloped borders, poor circumscription, and variations in color of predominantly tan to brown Fig. 1A . Some such macular lesions become patches that are increasingly asymmetrical, poorly circumscribed, and varied in color Fig. 1B ....

Pigmented Spindle Cell Melanocytic Tumor

The pigmented spindle cell tumor PSCT is considered by some to be a pigmented variant of Spitz tumor, and it is clear that clinical and histological overlap occurs between the two lesions. However, the PSCT may show rather distinctive attributes in a large proportion of cases. The lesion usually presents as a small well-defined dark brown to black flat topped papule Fig. 11A . Histologically, PSCT is a sharply circumscribed mainly intraepidermal proliferation of small heavily pigmen-ted...