Nxy059

,NH4

OH Tempol

Figure 3 Chemical structures of nitrone-containing 'spin traps' that have been shown to be neuroprotective in models of CNS injury and/or stroke.

MDL 101, 202

Stilbazulenyl nitrone

Figure 3 Chemical structures of nitrone-containing 'spin traps' that have been shown to be neuroprotective in models of CNS injury and/or stroke.

Nitric oxide synthase

PG synthase 5-Lipoxygenase Mitochondrial leak Xanthine oxidase Dopamine oxidation Neutrophils Macrophages Microglia

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