Rcw

Fibrin monomers

I XIIa Fibrin polymer

Figure 2 Diagram showing the coagulation cascade. PL, phospholipids.

thrombin activation of the fibrinolytic pathway and the presence of antithrombin III, which prevents clotting factor activation, protein C, which inactivates factor Va, and protein S, which acts as a cofactor for protein C where they form a complex to inactivate factor VIIIa.3

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