Methods

Hemoglobin results for approximately 95,000 patients per quarter were included in this analysis. Patients were included regardless of modality (HD vs. PD), setting (in-center vs. home), admission status (permanent or transient), or medication use. No patients or laboratory results were excluded. For each time period, intra-patient 3-month averages were determined as the mean of all HGB values in the 3 months. For creation of histograms, the 3-month averages were rounded to the nearest 0.1 g/dl. Intra-patient 1-month HGB averages were also determined. The mean of the patient mean HGB was then calculated for trending.

EPO doses administered in-center are recorded for each dialysis treatment. Intra-patient 1-month averages were determined as the mean of all in-center doses in 1 month. The mean of the patient mean dose was then calculated for trending.

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