Acknowledgments

Most of our studies on WRN, RECQL4, and RECQL5 were carried out at the AGENE Research Institute that has been supported by the Drug Organization (The Organization for Drug ADR Relief, Research and Development Promotion and Product Review) supervised by the Ministry of Health and Welfare of the Japanese government. We are grateful for Dr. Koji Ichikawa for providing us with unpublished information on the RECQL4 knockout mouse. We thank Dr. No-ralane M. Lindor at the Mayo Clinic, Rochester, MN, for critical reading of the manuscript and for providing Figure 1. We also thank the John A. Hartford Foundation for giving us the opportunity to contribute to this publication.

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