Trafficking

An essential feature of all eukaryotic cells is their highly compartmentalized organization, which allows the spatial and temporal separation of the synthesis, modification, degradation, secretion, or take up of molecules. Each of the various organelles within cells is specialized for one or more tasks and therefore needs a specialized set of proteins to carry out its function. In this chapter we will examine how a protein, once synthesized on a ribosome, is precisely and actively moved (translocated) to the correct cellular compartment.

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