Association of Increases in Troponin With Outcomes in Sepsis

Higher cardiac troponin concentrations in patients with sepsis have been associated with higher mortality (Fig. 4) in a few published studies to date (30). Such patients are also more likely to have other markers of a less favorable clinical status as captured by critical care indices of severity of illness (e.g., APACHE II score). Therefore, it is not yet clear whether troponin is an independent predictor of poor outcomes in sepsis.

Hours Days

Fig. 4. Median serum cTnT concentrations for survivors (dotted line) and nonsurvivors (solid line) in patients with sepsis during ICU stay. (Reproduced from ref. 30.)

Hours Days

Fig. 4. Median serum cTnT concentrations for survivors (dotted line) and nonsurvivors (solid line) in patients with sepsis during ICU stay. (Reproduced from ref. 30.)

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