Dosage

Please refer to regimens outlined in the CLL section

Cladribine -as therapy for low-grade or mantle cell lymphoma (2-CdA) 2-CdA 5 mg/M2 IV days 1-3

mitoxantrone Mitoxantrone 8 mg/M2 IV days 1-2

-mitoxantrone dose is reduced to 12 mg/M2 on day 1 only if previously treated

REF: Rummel et al. Blood 1999; 94(Suppl 1):abstract 2931

PREMEDICATIONS

1. Compazine 10 mg PO/IV 30 minutes before chemotherapy on days 1-3

Repeat every 28 days

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